What medicine can be used to remove chloasma?
Melasma is a common skin pigmentation problem that mostly occurs on the face, especially on the cheekbones, forehead and upper lip. In the past 10 days, there has been a lot of discussion on the Internet about treatment methods for chloasma, especially drug treatment options. This article will combine recent hot topics and authoritative information to provide you with structured data to help you understand the drug treatment options for melasma.
1. Causes of chloasma

The causes of chloasma are complex and are mainly related to the following factors:
| Cause | illustrate |
|---|---|
| UV irradiation | Long-term exposure to sunlight stimulates the activity of melanocytes |
| Hormone changes | Pregnancy, oral contraceptives, etc. can cause estrogen levels to increase |
| genetic factors | People with a family history of chloasma are more likely to develop the disease |
| skin inflammation | Pigmentation may be induced after certain skin diseases or skin injuries |
2. Drug treatment options for chloasma
The following are the melasma drug treatment options that have been highly discussed on the Internet in the past 10 days:
| drug type | Representative medicine | Mechanism of action | life cycle | Things to note |
|---|---|---|---|---|
| topical hydroquinone | 2%-4% hydroquinone cream | Inhibit tyrosinase activity | 3-6 months | Use away from light, skin irritation may occur |
| Vitamin A acids | Vitamin A acid cream | Promote keratin metabolism | more than 3 months | Need to be used at night, pregnant women are prohibited |
| Vitamin C | L-vitamin C | Antioxidant, inhibit melanin | long term use | Need to choose stable formula |
| tranexamic acid | Oral or topical preparations | Inhibit melanin formation | 3-6 months | Need to be used under the guidance of a doctor |
| compound preparation | Triple cream (hydroquinone + retinoic acid + hormone) | Multiple mechanisms of action | 4-8 weeks | Medical advice must be strictly followed |
3. Recent hot topics of discussion
1.New applications of tranexamic acid: Recent studies have shown that low-dose oral tranexamic acid has a significant effect on refractory chloasma, which has become a hot topic of discussion.
2.The rise of natural ingredients: Products containing natural ingredients such as arbutin and licorice extract are favored by consumers, but experts remind you to pay attention to the actual concentration and effect.
3.Combination therapy trends: Drug + photoelectric combined treatment has become a new trend, which can improve efficacy and reduce side effects.
4. Precautions for drug treatment
| Things to note | Detailed description |
|---|---|
| Sun protection is crucial | Strict sun protection must be used during any drug treatment, SPF50+ |
| step by step | Medication effects usually take 4-8 weeks to appear |
| Skin sensitivity test | New medicines should be tested on a small area of skin before using them |
| Avoid self-medication | Some medicines require a doctor's prescription and cannot be purchased and used by yourself. |
| Use with caution during pregnancy | Most freckle removal drugs are contraindicated during pregnancy |
5. Expert advice
1. Chloasma treatment requires patience, and it usually takes 3-6 months to see obvious results.
2. It is recommended to go to the dermatology department of a regular hospital first to make a clear diagnosis before choosing a treatment plan.
3. The effect will be better when drug treatment is combined with lifestyle adjustments (such as sun protection, stress reduction, and regular work and rest).
4. For stubborn chloasma, combined photoelectric therapy can be considered, but it needs to be performed by an experienced doctor.
6. Summary
There are various drug treatment options for melasma, and recently tranexamic acid and compound preparations have become hot topics of discussion. No matter which option you choose, you need to stick to it and combine it with strict sun protection measures. It is recommended to formulate a personalized treatment plan under the guidance of a professional doctor and avoid blindly following the trend of using Internet celebrity products. Remember, melasma treatment is a long-term process, and you need to be patient and scientific to achieve the desired results.
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